Benzodiazepine Stability in Postmortem Samples Stored at Different Temperatures

Benzodiazepine stability in postmortem samples stored at different temperatures.

Benzodiazepine (lorazepam, estazolam, chlordiazepoxide, and ketazolam) stability was studied in postmortem blood, bile, and vitreous humor stored at different temperatures over six months. The influence of NaF, in blood and bile samples, was also investigated. A solid-phase extraction technique was used on all the studied samples, and benzodiazepine quantification was performed by high-performa...

Stability of rabies suckling mouse brain vaccine stored at different temperatures.

Rabies in man and animals continues to be a serious problem for public health and the livestock economy in most countries of Latin America and the Caribbean (I). Between 1980 and 1985 this area had a total of 1,744 registered rabies cases in humans, 83,858 in dogs, 6,876 in cats, and 28,800 in cattlealthough a considerable share of the bovine cases are usually not reported (2). According to dat...

Spectrophotometric Study of Stability Constants of Metal Complexes of Promethazine at Different Temperatures

The complexation reactions between Cu2+, Pd2+ and Ni2+ metal ions with promethazine (PM) in water or DMF were studied by the spectrophotometric methods at [(15, 25,35 and 45±0.1) °C]. The complexation process was optimized in terms of pH, temperature and contact time. The stoichiometry of the complex was found to be 1:1 (metal ion/ligand). The formation constants of the resulting complexes were...

Some Chemical Changes Exhibited in Sterile and in Contaminated Haddock Muscle Stored at Different Temperatures.

The bio-chemical changes which occur in fish tissues are due to two factors, autolysis and bacterial action. As early as 1903, Muller reported that changes due to autolysis took place when sterile fish tissues were incubated. More recently attention has been focussed on the relative importance of these two causes of bio-chemical change. Reed, Rice and Sinclair (1929) presented evidence that aut...

Modeling the Survival of Salmonella in Soy Sauce-Based Products Stored at Two Different Temperatures